MOTS-C 100mg
Original price was: $ 540.00.$ 300.00Current price is: $ 300.00.
MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA type-C) is a small mitochondrial-derived peptide that plays a key role in regulating metabolism, stress responses, and cellular homeostasis.
| Category | |
|---|---|
| Substance | MOTS-C |
| Dosage | 100mg 10x10mg |
| Manufacturer | AP Labs |
| Warehouse | Bulk Peptides |
MOTS-C
MOTS-C is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA gene, making it one of the mitochondrial-derived peptides (MDPs). Unlike typical mitochondrial proteins, which are translated from nuclear DNA and imported into mitochondria, MOTS-C originates directly from mitochondrial DNA, highlighting the organelle’s role in signaling beyond energy production.
Research shows that MOTS-C acts as a metabolic regulator, influencing processes such as insulin sensitivity, glucose uptake, fatty acid oxidation, and protection against metabolic stress. It helps maintain cellular homeostasis by activating the AMPK pathway, a key energy sensor that balances anabolic and catabolic processes.
MOTS-C has also been shown to translocate to the nucleus during metabolic or oxidative stress, where it can regulate the expression of stress-response genes. This unique “mitonuclear communication” allows mitochondria to influence cellular adaptation and survival under adverse conditions.
Clinically, MOTS-C has attracted interest for its potential role in treating age-related diseases, obesity, type 2 diabetes, cardiovascular diseases, and even exercise mimetics. Studies suggest that circulating MOTS-C levels decline with age, linking it to aging-related decline in metabolic health and resilience.
In summary, MOTS-C is not just a byproduct of mitochondria but a critical signaling molecule that integrates metabolism, stress resistance, and longevity pathways, making it a promising target for future therapeutic interventions.
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Product only ships USA to USA. If you want to order this for another region International or EU/UK, reach out to us via email or live chat. MOQ will be 10 kits.
