PT-141 100mg

PT-141

PT-141, also known as Bremelanotide, is a synthetic analog of the melanocortin peptide hormone α-MSH (alpha-melanocyte-stimulating hormone). It was originally developed while studying tanning agents like Melanotan II, but researchers discovered that it had powerful effects on sexual arousal independent of sun exposure.

Unlike drugs such as sildenafil (Viagra), which act on the vascular system by increasing blood flow, PT-141 works at the central nervous system level. Specifically, it binds to melanocortin-4 receptors (MC4R) in the brain, which are involved in sexual desire and arousal pathways. This makes PT-141 unique because it directly stimulates the neural circuits of libido rather than just improving circulation.

Key features of PT-141:

• Men: Investigated for erectile dysfunction, especially in cases where PDE5 inhibitors (like Viagra or Cialis) are less effective.

• Women: Approved by the FDA (as Bremelanotide) for premenopausal women with hypoactive sexual desire disorder (HSDD).

• Mechanism: Activates central melanocortin pathways → boosts sexual motivation and arousal.

• Administration: Commonly delivered via subcutaneous injection or nasal spray.

• Duration: Effects may last up to several hours after dosing.

Clinical studies have shown PT-141 to be generally well-tolerated, with side effects mainly including nausea, flushing, and increased blood pressure in some users.

In summary, PT-141 is a centrally acting sexual health peptide that enhances libido and arousal by stimulating melanocortin receptors in the brain, making it distinct from blood-flow–based treatments and a promising option for both men and women with sexual dysfunction.